Inhalation of Buffered GSH: A Case Report



Note: Please consult with your medical professional before undertaking any changes to your medical treatment or that of your dependents. The UVICF strongly recommends that no one try this therapy without the consent and supervision of their medical professionals.

With the advent of GSH Plus, a form of GSH that is pH adjusted to pH 5.5 and when mixed according to directions yields an approximately isotonic solution, many of the problems of the inhalation of GSH noted with free acid GSH have vanished. Those who have used the product have experienced virtually no bronchoconstriction, and or other negative side effects.

We are pleased to tell you of one remarkable case. The CF patient in question, T., does not reside in North America, and is using both oral GSH and inhaled buffered GSH Plus under the supervision of a CF doctor. No other significant changes to T.'s medical regimen were made during the time period (1999-2000) in question.

DATE FEV1 FVC FEF 25-75 Days of GSH Use
9-15-99 0.26 0.43 0.17 0
10-4-99 0.31 0.55 0.16 3 (inhaled)
10-18-99 0.37 0.74 0.14 17 (inhaled), 3 (oral)
11-8-99 0.39 0.68 0.21 38 (inhaled), 24 (oral)
12-8-99 0.50 0.82 0.31 66 (inhaled), 52 (oral)
1-10-00 0.54 0.80 0.36 99 (inhaled), 85 (oral)